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Journal Club

Joshua Holmes
Joshua Holmes
March 15, 2023 8:45 a.m.
School of Medicine E501
Mentor: Julian E. Stelzer, PhD

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JOURNAL CLUB

"Membrane phosphoinositides regulate GPCR-β-arrestin complex assembly and dynamics"

Cell 2022, 185, 4560–4573      https://doi.org/10.1016/j.cell.2022.10.018     https://www.cell.com/cell/fulltext/S0092-8674(22)01360-5

John Janetzko,1 Ryoji Kise,2 Benjamin Barsi-Rhyne,3,4 Dirk H. Siepe,1,5,6 Franziska M. Heydenreich,1 Kouki Kawakami,2 Matthieu Masureel,1,7 Shoji Maeda,1,8 K. Christopher Garcia,1,5,6 Mark von Zastrow,3,4 Asuka Inoue,2,* and Brian K. Kobilka,1,9,*

1Department of Molecular and Cellular Physiology, Stanford University School of Medicine, Stanford, CA 94305, USA
2Graduate School of Pharmaceutical Sciences, Tohoku University, 6-3, Aoba, Aramaki, Aoba-ku, Sendai, Miyagi 980-8578, Japan
3Department of Cellular and Molecular Pharmacology, University of California, San Francisco, School of Medicine, San Francisco, CA
94158, USA
4Department of Psychiatry, University of California, San Francisco, School of Medicine, San Francisco, CA 94158, USA
5Department of Structural Biology, Stanford University School of Medicine, Stanford, CA 94305, USA
6Howard Hughes Medical Institute, Stanford University School of Medicine, Stanford, CA 94305, USA
7Present address: Department of Structural Biology, Genentech Inc., South San Francisco, CA 94080, USA
8Present address: Department of Pharmacology, University of Michigan Medical School, Ann Arbor, MI 48109, USA
9Lead contact
*Correspondence: iaska@tohoku.ac.jp (A.I.), kobilka@stanford.edu (B.K.K.)